The Institute for Drugs-Herbal Medicine-Excipient Research and Development (ID-HED-ERD) was a product of a proposal submitted to the University of Nigeria Senate by the Faculty of Pharmaceutical Sciences in 2016. The Faculty submitted two proposed institutes – one dealing with Drug Development and Herbal Medicine and the other dealing with research into Pharmaceutical excipients. The University Senate merged the two proposed institutes to what is now known as Institute for Drug-Herbal Medicine-Excipient Research and Development. The Institute was approved as one of the Research Institutes in the University of Nigeria, and domiciled in the Faculty of Pharmaceutical Sciences at the 388th meeting of the University Senate on August 31, 2016. The Institute received a formal approval by the University Governing Council at its 250th meeting held in January 17 and 18, 2017.
On March 10, 2017 the Vice Chancellor, Professor B.C Ozumba appointed Professor Sabinus Ifeanyi Ofoefule, a Professor of Pharmaceutical Technology and Industrial Pharmacy as the Pioneer Director of the Institute.